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  • Anti-PARP Monoclonal Antibody
产品名称:

Anti-PARP Monoclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-PARP Monoclonal Antibody
应用 WB IHC
稀释比例WB 1:1000-3000. IHC 1:200-500.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K200026M
规格50ul/100ul供货周期现货
主要用途WB IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-PARP Monoclonal Antibody 

英文名称Anti-PARP Monoclonal Antibody
宿主Mouse
别名PARP-1; Poly(ADP ribose) polymerase 1; sPARP1;ADPRT1; ADP ribosyltransferase NAD(+)
应用WB IHC
稀释比例WB 1:1000-3000. IHC 1:200-500.
交叉反应Human
蛋白分子量116kDa
Gene ID142
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG1
免疫原A synthetic peptide coupled to KLH
性状液体
Public Immunogen Range

A synthetic peptide coupled to KLH

Subcellular LocationsNucleus
Swiss ProtP09874
克隆号M3
克隆类型Monoclonal Antibody
背景资料Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.

 

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