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  • Anti-NFKB p65 Monoclonal Antibody
产品名称:

Anti-NFKB p65 Monoclonal Antibody

产品品牌: 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-NFKB p65 Monoclonal Antibody
应用 WB IHC IP
稀释比例WB 1:1000-3000. IP 1:100-300. IF 1:100-200. IHC 1:200-500.
交叉反应 Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K200045M
规格50ul/100ul供货周期现货
主要用途WB IHC IP应用领域医疗卫生,环保,化工,生物产业,农业

Anti-NFKB p65 Monoclonal Antibody

英文名称Anti-NFKB p65 Monoclonal Antibody
宿主Mouse
别名MGC131774;NFKB 3;NFKB3;TF65_HUMAN
应用WB IHC IP
稀释比例WB 1:1000-3000. IP 1:100-300. IF 1:100-200. IHC 1:200-500.
蛋白分子量65kDa
Gene ID5970
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG1
免疫原recombinant protein
性状液体
Public Immunogen Range

recombinant protein

Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ04206
克隆号5G6
克隆类型Monoclonal Antibody
背景资料NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.

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