Anti-EGFR Monoclonal Antibody
应用 WB IP IF
稀释比例WB 1:1000-3000. IP 1:100-300. IF 1:100-200.
交叉反应Human

产品型号：K200028M

更新时间：2022-08-15

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Anti-EGFR Monoclonal Antibody

英文名称	Anti-EGFR Monoclonal Antibody
宿主	Mouse
别名	Epidermal growth factor receptor;erbb 1;Receptor tyrosine protein kinase ErbB 1
应用	WB IP IF
稀释比例	WB 1:1000-3000. IP 1:100-300. IF 1:100-200.
交叉反应	Human
蛋白分子量	170kDa
Gene ID	1956
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	A synthetic peptide coupled to KLH
性状	液体
Public Immunogen Range	A synthetic peptide coupled to KLH
Subcellular Locations	Secreted Cell membrane
Swiss Prot	P00533
克隆号	M6
克隆类型	Monoclonal Antibody
背景资料	The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.