欢迎光临北京索莱宝科技有限公司网站!
销售咨询热线:
您的位置: 网站首页 > 产品中心 > 抗体 > Monoclonal Antibody > K200050MAnti-EGFR Monoclonal Antibody
  • Anti-EGFR Monoclonal Antibody
产品名称:

Anti-EGFR Monoclonal Antibody

产品品牌: 索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-EGFR Monoclonal Antibody
应用 WB IF IHC
稀释比例WB 1:500-2000. IF 1:100-200. IHC 1:200-500.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K200050M
规格50ul/100ul供货周期现货
主要用途WB IF IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-EGFR Monoclonal Antibody

英文名称Anti-EGFR Monoclonal Antibody
宿主Mouse
别名Epidermal growth factor receptor;erbb 1;Receptor tyrosine protein kinase ErbB 1
应用WB IF IHC
稀释比例WB 1:500-2000. IF 1:100-200. IHC 1:200-500.
交叉反应Human
蛋白分子量170kDa
Gene ID1956
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG1
免疫原A synthetic peptide coupled to KLH
性状液体
Public Immunogen RangeA synthetic peptide coupled to KLH
Subcellular LocationsNucleus Endosome Plasma membrane Golgi apparatus Endoplasmic reticulum secreted
Swiss ProtP00533
克隆号1B1
克隆类型Monoclonal Antibody
背景资料The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascadesβ-Actin is one of six different actin isoforms that have been identified. The actin molecules found in cells of various species and tissues tend to be very similar in their immunological and physical properties. Therefore, Antibodies against β-Actin are useful as loading controls for Western Blotting. However it should be noted that levels of β-Actin may not be stable in certain cells. For example, expression of β-Actin in adipose tissue is very low and therefore β-Actin should not be used as loading control for these tissues.

 

留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7