北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K200021M
更新时间：2022-08-15
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| 英文名称 | Anti-NSE Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | Enolase 2;Neuron specific gamma enolase;ENOG;Eno 2 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 47kDa |
| Gene ID | 2026 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P09104 |
| 克隆号 | 1.30E+03 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. |
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