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  • Anti-HSP70 Monoclonal Antibody
产品名称:

Anti-HSP70 Monoclonal Antibody

产品品牌: 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-HSP70 Monoclonal Antibody
应用 WB IF
稀释比例WB 1:1000-2000. IF 1:100-200.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K200048M
规格50ul/100ul供货周期现货
主要用途WB IF应用领域医疗卫生,环保,化工,生物产业,农业

Anti-HSP70 Monoclonal Antibody

英文名称Anti-HSP70 Monoclonal Antibody
宿主Mouse
别名heat shock protein 70
应用WB IF
稀释比例WB 1:1000-2000. IF 1:100-200.
交叉反应Human Mouse Rat
蛋白分子量70kDa
Gene ID3303/3304
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG1
免疫原A synthetic peptide coupled to KLH
性状液体
Public Immunogen Range

A synthetic peptide coupled to KLH

Subcellular LocationsCytoplasm
Swiss ProtP0DMV8/P0DMV9
克隆号3G10
克隆类型Monoclonal Antibody
背景资料The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis.

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