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  • Anti-GCR Polyclonal Antibody
产品名称:

Anti-GCR Polyclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-GCR Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K101529P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-GCR Polyclonal Antibody

英文名称Anti-GCR Polyclonal Antibody
宿主Rabbit
别名GCCR;GCR;GCRST;GR;GRL
应用WB
稀释比例WB 1:3000.
交叉反应Human
蛋白分子量86kDa
Gene ID2908
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human GCR
性状液体
Public Immunogen Range

A synthetic peptide of human GCR

Subcellular LocationsCytoplasm Mitochondrion Nucleus Nucleus
Swiss ProtP04150
克隆类型Polyclonal Antibody
背景资料

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.

 

Anti-GCR Polyclonal Antibody

 

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