北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K101524P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：977
010-50973130
产品分类
Anti-TIMP1 Polyclonal Antibody
| 英文名称 | Anti-TIMP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ABH;ABH1;ALKBH;alkB;hABH |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human |
| 蛋白分子量 | 33kDa |
| Gene ID | 7076 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TIMP1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TIMP1 |
| Subcellular Locations | Secreted |
| Swiss Prot | P01033 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. |
当前位置：
上一个：
返回列表
