北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K101544P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-BMP2 Polyclonal Antibody
| 英文名称 | Anti-BMP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACAA;PTHIO;THIO;BMP-2A;BDA2 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Mouse |
| 蛋白分子量 | 45kDa |
| Gene ID | 12156 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BMP2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BMP2 |
| Subcellular Locations | secreted |
| Swiss Prot | P21274 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. |
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