北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106419P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：1007
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产品分类
Anti-DLG4 Polyclonal Antibody
| 英文名称 | Anti-DLG4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PSD95;SAP-90;SAP90;Disks large homolog 4;Postsynaptic density protein 95 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 85kDa |
| Gene ID | 1742 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human DLG4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human DLG4 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P78352 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity). |
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