
产品型号:K106417P
更新时间:2022-08-15
厂商性质:生产厂家
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产品分类
Anti-CADH2 Polyclonal Antibody
| 英文名称 | Anti-CADH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDH2;Cadherin-2;CDw325;CDHN;NCAD;CD325 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human |
| 蛋白分子量 | 10kDa |
| Gene ID | 1000 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CADH2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CADH2 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | P19022 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). |