北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106480P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：1052
010-50973130
产品分类
Anti-CD130 Polyclonal Antibody
| 英文名称 | Anti-CD130 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDW130;GP130;IL-6RB;IL6ST;IL-6R beta |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 65/125kDa |
| Gene ID | 3572 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CD130 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CD130 |
| Subcellular Locations | Cell membrane Nucleus Extracellular matrix |
| Swiss Prot | P40189 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. |
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