品牌 | SOLARBIO/索莱宝 | 货号 | K106480P |
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规格 | 50ul/100ul | 供货周期 | 现货 |
主要用途 | WB | 应用领域 | 医疗卫生,环保,化工,生物产业,农业 |
Anti-CD130 Polyclonal Antibody
英文名称 | Anti-CD130 Polyclonal Antibody |
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宿主 | Rabbit |
别名 | CDW130;GP130;IL-6RB;IL6ST;IL-6R beta |
应用 | WB |
稀释比例 | WB 1:3000. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 65/125kDa |
Gene ID | 3572 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human CD130 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human CD130 |
Subcellular Locations | Cell membrane Nucleus Extracellular matrix |
Swiss Prot | P40189 |
克隆类型 | Polyclonal Antibody |
背景资料 | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. |