北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106473P
更新时间：2022-08-15
厂商性质：生产厂家
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Anti-IL12 Polyclonal Antibody
| 英文名称 | Anti-IL12 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 3592 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL12 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL12 |
| Subcellular Locations | Cell membrane Secreted |
| Swiss Prot | P29459 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
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