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  • Anti-IL12 Polyclonal Antibody
产品名称:

Anti-IL12 Polyclonal Antibody

产品品牌: 索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-IL12 Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K106473P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-IL12 Polyclonal Antibody

英文名称Anti-IL12 Polyclonal Antibody
宿主Rabbit
别名IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A
应用WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat
蛋白分子量52kDa
Gene ID3592
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human IL12
性状液体
Public Immunogen RangeA synthetic peptide of human IL12
Subcellular LocationsCell membrane Secreted
Swiss ProtP29459
克隆类型Polyclonal Antibody
背景资料IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

 

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