北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106458P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：1050
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产品分类
Anti-MYC Polyclonal Antibody
| 英文名称 | Anti-MYC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BHLHE39;c-Myc;MRTL;MYCC |
| 应用 | WB IHC |
| 稀释比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 4609 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MYC |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MYC |
| Swiss Prot | P01106 |
| Subcellular Locations | Nucleus Cytoplasm |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
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