品牌 | SOLARBIO/索莱宝 | 货号 | K106494P |
---|---|---|---|
规格 | 50ul/100ul | 供货周期 | 现货 |
主要用途 | WB IHC | 应用领域 | 医疗卫生,环保,化工,生物产业,农林牧渔 |
Anti-SOCS1 Polyclonal Antibody
英文名称 | Anti-SOCS1 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
别名 | CIS1;CISH1;JAB;SOCS-1;SSI-1;SSI1;TIP-3;TIP3 |
应用 | WB IHC |
稀释比例 | WB 1:2000-5000.IHC 1:50-200. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 33kDa |
Gene ID | 8651 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human SOCS1 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human SOCS1 |
Subcellular Locations | Cytoplasm |
Swiss Prot | O15524 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |