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当前位置:首页产品中心抗体Polyclonal AntibodyK106486PAnti-SIRT1 Polyclonal Antibody

Anti-SIRT1 Polyclonal Antibody
产品简介:

Anti-SIRT1 Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat

产品型号:K106486P

更新时间:2022-08-15

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产品介绍

Anti-SIRT1 Polyclonal Antibody

英文名称Anti-SIRT1 Polyclonal Antibody
宿主Rabbit
别名SIR2;SIR2alpha;SIR2L1;SIR2-like protein 1;Hsir2
应用WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat
蛋白分子量130kDa
Gene ID23411
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human SIRT1
性状液体
Public Immunogen RangeA synthetic peptide of human SIRT1
Subcellular LocationsCytoplasm Nucleus Mitochondrion
Swiss ProtQ96EB6
克隆类型Polyclonal Antibody
背景资料This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

 

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