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  • Anti-LAMP1 Polyclonal Antibody
  • Anti-LAMP1 Polyclonal Antibody
产品名称:

Anti-LAMP1 Polyclonal Antibody

产品品牌: SOLARBIO/索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-LAMP1 Polyclonal Antibody
应用 WB IHC
稀释比例WB 1:2000-5000.IHC 1:50-200.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K106533P
规格50ul/100ul供货周期现货
主要用途WB IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-LAMP1 Polyclonal Antibody

英文名称Anti-LAMP1 Polyclonal Antibody
宿主Rabbit
别名CD107a;LAMPA;LGP120;lgpA;OTTHUMP00000040663
应用WB IHC
稀释比例WB 1:2000-5000.IHC 1:50-200.
交叉反应Human Mouse Rat
蛋白分子量40kDa
Gene ID3916
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human LAMP1
性状液体
Public Immunogen RangeA synthetic peptide of human LAMP1
Subcellular LocationsCell membrane Endosome membrane Late endosome Lysosome membrane Single-pass type I membrane protein
Swiss ProtP11279
克隆类型Polyclonal Antibody
背景资料Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

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