品牌 | SOLARBIO/索莱宝 | 货号 | K106519P |
---|---|---|---|
规格 | 50ul/100ul | 供货周期 | 现货 |
主要用途 | WB | 应用领域 | 医疗卫生,环保,生物产业,农林牧渔 |
Anti-NQO1 Polyclonal Antibody
英文名称 | Anti-NQO1 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
别名 | DHQU;DIA4;DTD;NMOR1;NMORI;QR1 |
应用 | WB |
稀释比例 | WB 1:3000. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 27kDa |
Gene ID | 1728 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human NQO1 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human NQO1 |
Subcellular Locations | Cytoplasm Cell membrane |
Swiss Prot | P15559 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |