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当前位置:首页产品中心抗体Polyclonal AntibodyK106513PAnti-VCAM-1 Polyclonal Antibody

Anti-VCAM-1 Polyclonal Antibody
产品简介:

Anti-VCAM-1 Polyclonal Antibody
应用 WB IHC
稀释比例WB 1:2000-5000.IHC 1:50-200.
交叉反应Human Mouse Rat

产品型号:K106513P

更新时间:2022-08-15

厂商性质:生产厂家

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产品介绍

Anti-VCAM-1 Polyclonal Antibody

英文名称Anti-VCAM-1 Polyclonal Antibody
宿主Rabbit
别名INCAM-100;CD106;CUL 5;Cullin5;CUL5_HUMAN
应用WB IHC
稀释比例WB 1:2000-5000.IHC 1:50-200.
交叉反应Human Mouse Rat
蛋白分子量81kDa
Gene ID7412
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human VCAM-1
性状液体
Public Immunogen RangeA synthetic peptide of human VCAM-1
Subcellular LocationsCytoplasm Nucleus Cell membrane
Swiss ProtP19320
克隆类型Polyclonal Antibody
背景资料VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells.

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