北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106513P
更新时间：2022-08-15
厂商性质：生产厂家
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Anti-VCAM-1 Polyclonal Antibody
| 英文名称 | Anti-VCAM-1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | INCAM-100;CD106;CUL 5;Cullin5;CUL5_HUMAN |
| 应用 | WB IHC |
| 稀释比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 7412 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human VCAM-1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human VCAM-1 |
| Subcellular Locations | Cytoplasm Nucleus Cell membrane |
| Swiss Prot | P19320 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
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