北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106549P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-IL2 Polyclonal Antibody
| 英文名称 | Anti-IL2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL-2;lymphokine;TCGF;Interleukin-2;T-cell growth factor |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 18kDa |
| Gene ID | 3558 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL2 |
| Subcellular Locations | Secreted |
| Swiss Prot | P60568 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
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