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当前位置:首页产品中心抗体Polyclonal AntibodyK106547PAnti-CD105 Polyclonal Antibody

Anti-CD105 Polyclonal Antibody
产品简介:

Anti-CD105 Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat

产品型号:K106547P

更新时间:2022-08-15

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产品介绍

Anti-CD105 Polyclonal Antibody

英文名称Anti-CD105 Polyclonal Antibody
宿主Rabbit
别名END;HHT1;ORW1;ENG;Endoglin
应用WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat
蛋白分子量53kDa
Gene ID2022
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human CD105
性状液体
Public Immunogen RangeA synthetic peptide of human CD105
Subcellular LocationsMembrane Single-pass type I membrane protein
Swiss ProtP17813
克隆类型Polyclonal Antibody
背景资料This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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