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  • Anti-PTEN Polyclonal Antibody
产品名称:

Anti-PTEN Polyclonal Antibody

产品品牌: 索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-PTEN Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K106537P
规格50ul /100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-PTEN Polyclonal Antibody

英文名称Anti-PTEN Polyclonal Antibody
宿主Rabbit
别名10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;PTENbeta;TEP1
应用WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat
蛋白分子量47kDa
Gene ID5728
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human PTEN
性状液体
Public Immunogen RangeA synthetic peptide of human PTEN
Subcellular LocationsCytoplasm Nucleus PML body Secreted
Swiss ProtP60484
克隆类型Polyclonal Antibody
背景资料This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

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