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  • Anti-ERK1/2 Polyclonal Antibody
产品名称:

Anti-ERK1/2 Polyclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-ERK1/2 Polyclonal Antibody
应用 WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K106589P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-ERK1/2 Polyclonal Antibody

英文名称Anti-ERK1/2 Polyclonal Antibody
宿主Rabbit
别名ERK;ERK-2;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2
应用WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse Rat
蛋白分子量41kDa
Gene ID5594
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ERK1/2
性状液体
Public Immunogen RangeRecombinant protein of human ERK1/2
Subcellular LocationsCytoplasm Nucleus Cell membrane Cytoskeleton
Swiss ProtP28482
克隆类型Polyclonal Antibody
背景资料Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.

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