北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106584P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：1030
010-50973130
产品分类
| 英文名称 | Anti-TLR4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARMD10;CD284;TLR-4;TOLL |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 73kDa |
| Gene ID | 7099 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TLR4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TLR4 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | O00206 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. |
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