产品型号:K106581P
更新时间:2022-08-15
厂商性质:生产厂家
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产品分类
Anti-HSP90 Polyclonal Antibody
英文名称 | Anti-HSP90 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
别名 | HSP90AA1;EL52;HEL-S-65p;Hsp103;HSP86;Hsp89;HSP89A |
应用 | WB |
稀释比例 | WB 1:500-2000. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 90kDa |
Gene ID | 3320 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human HSP90 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human HSP90 |
Subcellular Locations | Cytoplasm Nucleus Cell membrane |
Swiss Prot | P07900 |
克隆类型 | Polyclonal Antibody |
背景资料 | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation.Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation |