Anti-LIFR Polyclonal Antibody

英文名称	Anti-LIFR Polyclonal Antibody
宿主	Rabbit
别名	CD118;LIF-R;SJS2;STWS;SWS
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Human
蛋白分子量	115kDa
Gene ID	3977
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human LIFR
性状	液体
Public Immunogen Range	A synthetic peptide of human LIFR
Subcellular Locations	Cytoplasm Cell membrane
Swiss Prot	P42702
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.