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当前位置:首页产品中心抗体Polyclonal AntibodyK106613PAnti-LIFR Polyclonal Antibody

Anti-LIFR Polyclonal Antibody
产品简介:

Anti-LIFR Polyclonal Antibody
应用 WB
稀释比例WB 1:500-2000.
交叉反应Human

产品型号:K106613P

更新时间:2022-08-15

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产品介绍

Anti-LIFR Polyclonal Antibody

英文名称Anti-LIFR Polyclonal Antibody
宿主Rabbit
别名CD118;LIF-R;SJS2;STWS;SWS
应用WB
稀释比例WB 1:500-2000.
交叉反应Human
蛋白分子量115kDa
Gene ID3977
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human LIFR
性状液体
Public Immunogen RangeA synthetic peptide of human LIFR
Subcellular LocationsCytoplasm Cell membrane
Swiss ProtP42702
克隆类型Polyclonal Antibody
背景资料This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.

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