北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106613P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：977
010-50973130
产品分类
| 英文名称 | Anti-LIFR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD118;LIF-R;SJS2;STWS;SWS |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 115kDa |
| Gene ID | 3977 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human LIFR |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human LIFR |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P42702 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
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