北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106612P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-NR3C2 Polyclonal Antibody
| 英文名称 | Anti-NR3C2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MCR;MLR;MR;NR3C2VIT |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 107kDa |
| Gene ID | 4306 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NR3C2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NR3C2 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P08235 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |
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