北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106629P
更新时间：2022-08-15
厂商性质：生产厂家
访 问 量 ：868
010-50973130
产品分类
| 英文名称 | Anti-TERT Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EST2;TCS1;TRT;HEST2;TP2 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Mouse |
| 蛋白分子量 | 127kDa |
| Gene ID | 7015 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TERT |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TERT |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O14746 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. |
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