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  • Anti-BAX Polyclonal Antibody
产品名称:

Anti-BAX Polyclonal Antibody

产品品牌: 索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-BAX Polyclonal Antibody
应用 IHC
稀释比例IHC 1:50-200.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K106624P
规格50ul/100ul供货周期现货
主要用途IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-BAX Polyclonal Antibody

英文名称Anti-BAX Polyclonal Antibody
宿主Rabbit
别名Bcl2-L-4;Bax-protein;BAX_HUMAN;BAXA
应用IHC
稀释比例IHC 1:50-200.
交叉反应Human
蛋白分子量21kDa
Gene ID581
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human BAX
性状液体
Public Immunogen RangeA synthetic peptide of human BAX
Subcellular LocationsCytoplasm Cell membrane
Swiss ProtQ07812
克隆类型Polyclonal Antibody
背景资料Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.7

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    请输入计算结果(填写阿拉伯数字),如:三加四=7