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  • Anti-SMAD4 Polyclonal Antibody
产品名称:

Anti-SMAD4 Polyclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-SMAD4 Polyclonal Antibody
应用 WB
稀释比例WB 1:500-2000.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K106621P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-SMAD4 Polyclonal Antibody

英文名称Anti-SMAD4 Polyclonal Antibody
宿主Rabbit
别名DPC4;hSMAD4;JIP;MAD homolog 4;MADH4;Mothers against DPP homolog 4;SMAD 4;SMAD family member 4;SMAD4
应用WB
稀释比例WB 1:500-2000.
交叉反应Human
蛋白分子量60kDa
Gene ID4089
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human SMAD4
性状液体
Public Immunogen RangeRecombinant protein of human SMAD4
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ13485
克隆类型Polyclonal Antibody
背景资料This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.

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