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当前位置:首页产品中心抗体Polyclonal AntibodyK106619PAnti-MDH1 Polyclonal Antibody

Anti-MDH1 Polyclonal Antibody
产品简介:

Anti-MDH1 Polyclonal Antibody
应用 WB IHC
稀释比例WB 1:500-2000. IHC 1:25-100.
交叉反应Human Mouse

产品型号:K106619P

更新时间:2022-08-15

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产品介绍

Anti-MDH1 Polyclonal Antibody

英文名称Anti-MDH1 Polyclonal Antibody
宿主Rabbit
别名MDH1;HEL-S-32;MDH-s;MDHA;MGC:1375;MOR2
应用WB IHC
稀释比例WB 1:500-2000. IHC 1:25-100.
交叉反应Human Mouse
蛋白分子量36kDa
Gene ID4190
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human MDH1
性状液体
Public Immunogen RangeRecombinant protein of human MDH1
Subcellular LocationsCytoplasm
Swiss ProtP40925
克隆类型Polyclonal Antibody
背景资料This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6

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