北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106619P
更新时间：2022-08-15
厂商性质：生产厂家
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Anti-MDH1 Polyclonal Antibody
| 英文名称 | Anti-MDH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MDH1;HEL-S-32;MDH-s;MDHA;MGC:1375;MOR2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 36kDa |
| Gene ID | 4190 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MDH1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MDH1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P40925 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6 |
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