北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106634P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-PGH2 Polyclonal Antibody
| 英文名称 | Anti-PGH2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PTGS2;COX2;PHS II;PGHS-2 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 69kDa |
| Gene ID | 5743 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PGH2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PGH2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P35354 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. |
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