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当前位置:首页产品中心抗体Polyclonal AntibodyK106634PAnti-PGH2 Polyclonal Antibody

Anti-PGH2 Polyclonal Antibody
产品简介:

Anti-PGH2 Polyclonal Antibody
应用 IHC
稀释比例IHC 1:50-200.
交叉反应Human

产品型号:K106634P

更新时间:2022-08-15

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产品介绍

Anti-PGH2 Polyclonal Antibody

英文名称Anti-PGH2 Polyclonal Antibody
宿主Rabbit
别名PTGS2;COX2;PHS II;PGHS-2
应用IHC
稀释比例IHC 1:50-200.
交叉反应Human
蛋白分子量69kDa
Gene ID5743
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human PGH2
性状液体
Public Immunogen RangeA synthetic peptide of human PGH2
Subcellular LocationsCytoplasm
Swiss ProtP35354
克隆类型Polyclonal Antibody
背景资料Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

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