北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106633P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-EGLN Polyclonal Antibody
| 英文名称 | Anti-EGLN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ENG;END;CD105;Endoglin |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 71kDa |
| Gene ID | 2022 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EGLN |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human EGLN |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P17813 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors. |
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