产品型号:K106653P
更新时间:2022-08-15
厂商性质:生产厂家
访 问 量 :971
010-50973130
产品分类
Anti-Smad4 Polyclonal Antibody
英文名称 | Anti-Smad4 Polyclonal Antibody |
---|---|
宿主 | Rabbit |
别名 | DPC4;MADH4;Hsmad4;MAD homolog 4 |
应用 | IHC |
稀释比例 | IHC 1:50-200. |
交叉反应 | Mouse |
蛋白分子量 | 60kDa |
Gene ID | 4089 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | A synthetic peptide of human Smad4 |
性状 | 液体 |
Public Immunogen Range | A synthetic peptide of human Smad4 |
Subcellular Locations | Cytoplasm Nucleus |
Swiss Prot | Q13485 |
克隆类型 | Polyclonal Antibody |
背景资料 | In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. |