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  • Anti-MADH7 Polyclonal Antibody
产品名称:

Anti-MADH7 Polyclonal Antibody

产品品牌: SOLARBIO/索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-MADH7 Polyclonal Antibody
应用 IHC
稀释比例IHC 1:50-200.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K106646P
规格50ul/100ul供货周期现货
主要用途IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-MADH7 Polyclonal Antibody

英文名称Anti-MADH7 Polyclonal Antibody
宿主Rabbit
别名CRCS3;MADH7;MADH8;Hsmad7;MAD homolog 8
应用IHC
稀释比例IHC 1:50-200.
交叉反应Human
蛋白分子量46kDa
Gene ID4092
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human MADH7
性状液体
Public Immunogen RangeA synthetic peptide of human MADH7
Subcellular LocationsNucleus
Swiss ProtO15105
克隆类型Polyclonal Antibody
背景资料Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R1-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

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