北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106679P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-CASP8 Polyclonal Antibody
| 英文名称 | Anti-CASP8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALPS2B;CAP4;Casp-8;FLICE;MACH;MCH5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 55kDa |
| Gene ID | 841 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CASP8 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CASP8 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q14790 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. |
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