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当前位置:首页产品中心抗体Polyclonal AntibodyK106714PAnti-Thioredoxin Polyclonal Antibody

Anti-Thioredoxin Polyclonal Antibody
产品简介:

Anti-Thioredoxin Polyclonal Antibody
应用 IHC
稀释比例IHC 1:25-100.
交叉反应Human

产品型号:K106714P

更新时间:2022-08-15

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产品介绍

Anti-Thioredoxin Polyclonal Antibody

英文名称Anti-Thioredoxin Polyclonal Antibody
宿主Rabbit
别名TRDX;TRX;TRX1;TXN
应用IHC
稀释比例IHC 1:25-100.
交叉反应Human
蛋白分子量12kDa
Gene ID7295
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human Thioredoxin
性状液体
Public Immunogen RangeA synthetic peptide of human Thioredoxin
Subcellular LocationsNucleus Cytoplasm Secreted
Swiss ProtP10599
克隆类型Polyclonal Antibody
背景资料Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

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