北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106744P
更新时间：2022-08-14
厂商性质：生产厂家
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产品分类
Anti-AKR1C3 Polyclonal Antibody
| 英文名称 | Anti-AKR1C3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DDX;HAKRB;HSD17B5;KIAA0119;PGFS |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 37kDa |
| Gene ID | 8644 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AKR1C3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AKR1C3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P42330 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |
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