北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106740P
更新时间：2022-08-14
厂商性质：生产厂家
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Anti-JAB1 Polyclonal Antibody
| 英文名称 | Anti-JAB1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CSN5;JAB1;MOV-34;SGN5 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 38kDa |
| Gene ID | 10987 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human JAB1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human JAB1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q92905 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. |
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