
产品型号:K106784P
更新时间:2022-08-14
厂商性质:生产厂家
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产品分类
Anti-ITGAL Polyclonal Antibody
| 英文名称 | Anti-ITGAL Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD11A;LFA-1A |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 128kDa |
| Gene ID | 3683 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ITGAL |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ITGAL |
| Subcellular Locations | Cell membrane |
| Swiss Prot | P20701 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |