北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K000341P
更新时间：2022-08-13
厂商性质：生产厂家
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Anti-TARDBP Polyclonal Antibody
| 英文名称 | Anti-TARDBP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALS10;TDP-43 |
| 应用 | WB IHC IF IP RIP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:20-100. IP 1:50-100. RIP 1:20-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 23435 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TARDBP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TARDBP |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q13148 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
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