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  • Recombinant Human IL-15细胞因子
产品名称:

Recombinant Human IL-15细胞因子

产品品牌: SOLARBIO/索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2024-04-17
Recombinant Human Interleukin-15(Recombinant Human IL-15细胞因子) is produced by our E.coli expression system and the target gene encoding<br>Asn49-Ser162 is expressed.

产品概述

品牌SOLARBIO/索莱宝供货周期现货

Recombinant Human IL-15细胞因子 

Known asInterleukin-15; IL-15; IL15
Derived fromE.coli
PurityMeasured by the dose dependent stimulation of mouse CTLL-2 cell proliferation.ED50 is less than 0.5 ng/ml. Specific Activity of 2.0 x 10^6 IU/mg.Greater than 95% as determined by reducing SDS-PAGE.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 9 months
ReconstitutionAlways centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 7X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles.
EndotoxinLess than 0.1 ng/ug (1 IEU/ug).
Amino Acid SequenceNWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKE CEELEEKNIKEFLQSFVHIVQMFINTS
BackgroundHuman Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.

Recombinant Human Interleukin-15 is produced by our E.coli expression system and the target gene encoding Asn49-Ser162 is expressed.

 

Recombinant Human IL-15细胞因子订购说明:

1、绝大部分产品备有现货,一般情况下都能订货当日发货。 
2、部分非常用产品,需提前1-2日预订,海外期货则需要提前3-6周预订。 
3、部分产品价格会因货期、批次等因素发生变化,若有变动以订货当日新价格为准。 
4、每日订单截止时间为16点整,部分城市可到17点整,因超过截止时间造成当日不能发货的将于次日安排发货。
5、请办理完货款后,将底单等连同收货人的地址、姓名、等以传真、、短信、等形式通知我们。


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