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  • Anti-RUNX2 Polyclonal Antibody
产品名称:

Anti-RUNX2 Polyclonal Antibody

产品品牌: 索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-RUNX2 Polyclonal Antibody
应用 WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse

产品概述

品牌SOLARBIO/索莱宝货号K101309P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-RUNX2 Polyclonal Antibody

英文名称Anti-RUNX2 Polyclonal Antibody
宿主Rabbit
别名AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;OSF-2;OSF2;PEA2aA;PEBP2aA
应用WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse
蛋白分子量56kDa
Gene ID860
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human RUNX2
性状液体
Public Immunogen RangeA synthetic peptide of human RUNX2
Subcellular LocationsNucleus
Swiss ProtQ13950
克隆类型Polyclonal Antibody
背景资料Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.

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