北京索莱宝科技
专注于生物学试剂及试剂盒领域
服务热线：18101056239
专注于生物学试剂及试剂盒领域
服务热线：18101056239
产品型号：K106477P
更新时间：2022-08-15
厂商性质：生产厂家
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产品分类
Anti-XBP1 Polyclonal Antibody
| 英文名称 | Anti-XBP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TREB-5;XBP2;TREB5;XBP-1; |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 45kDa |
| Gene ID | 7494 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human XBP1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human XBP1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P17861 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). |
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