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  • Anti-XIAP Polyclonal Antibody
产品名称:

Anti-XIAP Polyclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-XIAP Polyclonal Antibody
应用 WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat

产品概述

品牌SOLARBIO/索莱宝货号K106527P
规格50ul/100ul供货周期现货
主要用途WB应用领域医疗卫生,环保,化工,生物产业,农业

Anti-XIAP Polyclonal Antibody

英文名称Anti-XIAP Polyclonal Antibody
宿主Rabbit
别名API3;BIRC4;hIAP-3;hIAP3;IAP-3;ILP1;MIHA;XLP2
应用WB
稀释比例WB 1:3000.
交叉反应Human Mouse Rat
蛋白分子量54kDa
Gene ID331
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原A synthetic peptide of human XIAP
性状液体
Public Immunogen RangeA synthetic peptide of human XIAP
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP98170
克隆类型Polyclonal Antibody
背景资料This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
 

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