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  • Anti-P27 Polyclonal Antibody
产品名称:

Anti-P27 Polyclonal Antibody

产品品牌: SOLARBIO/索莱宝 价格:
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-P27 Polyclonal Antibody
应用 IHC
稀释比例IHC 1:50-200.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K106720P
规格50ul/100ul供货周期现货
主要用途IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-P27 Polyclonal Antibody

英文名称Anti-P27 Polyclonal Antibody
宿主Rabbit
别名CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1
应用IHC
稀释比例IHC 1:50-200.
交叉反应Human
蛋白分子量22kDa
Gene ID1027
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human P27
性状液体
Public Immunogen RangeRecombinant protein of human P27
Subcellular LocationsNucleus
Swiss ProtP46527
克隆类型Polyclonal Antibody
背景资料This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)

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