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  • Anti-CDK4 Polyclonal Antibody
产品名称:

Anti-CDK4 Polyclonal Antibody

产品品牌: 索莱宝 价格: 960
厂商性质: 生产厂家 产品时间: 2022-08-15
Anti-CDK4 Polyclonal Antibody
应用 IHC
稀释比例IHC 1:50-200.
交叉反应Human

产品概述

品牌SOLARBIO/索莱宝货号K106719P
规格50ul/100ul供货周期现货
主要用途IHC应用领域医疗卫生,环保,化工,生物产业,农业

Anti-CDK4 Polyclonal Antibody 

英文名称Anti-CDK4 Polyclonal Antibody
宿主Rabbit
别名CDK4;Cell division protein kinase 4;CMM3;cyclin dependent kinase 4;PSK J3
应用IHC
稀释比例IHC 1:50-200.
交叉反应Human
蛋白分子量34kDa
Gene ID1019
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human CDK4
性状液体
Public Immunogen RangeRecombinant protein of human CDK4
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP11802
克隆类型Polyclonal Antibody
背景资料The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers.

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